Abstract:
Delivery of medicines and vaccines has been largely unchanged for the past 150 years, with hypodermic needles being the vector of choice. In contrast, there has been considerable innovation in drug development, with explosive growth in the field of injectables (i.e. liquid-based drugs delivered across the skin). In this talk, I will present my groups' recent work in this area, with the main focus on needle-free intradermal jet injection, where we use a combination of experimental (high-speed video) observations, theory and numerical simulations to elucidate fundamental fluid dynamics of the process. I will also briefly discuss my groups other efforts related to (i) laser-induced and spark-induced micro-jets, (ii) drop impact for ophthalmic drug delivery, and (iii) using tattoo devices for intradermal injection.
Bio:
Dr. Jeremy Marston joined Texas Tech as an assistant professor of Chemical Engineering in 2014 and was awarded tenure in 2020. Prior to this, he earned his BS-MS in Mathematical Science and Ph.D. in Chemical Engineering at the University of Birmingham in the UK and has worked as a research fellow at the Institute of Chemical and Engineering Science in Singapore, and as a research scientist at the King Abdullah University of Science and Technology in Saudi Arabia. Dr. Marston's research focuses on the application of high-speed imaging to fluid and granular flows, with emphasis on biomedical applications, such as needle-free transdermal drug delivery and ophthalmic drug delivery. He has received industrial funding from Inovio Pharmaceuticals and the NSF CAREER Award and has a portfolio of over 60 publications.