ABSTRACT: Conjugated polymers provide a unique toolbox for establishing electrical communication with biological systems. In the first half of this talk, I will introduce the type of conjugated polymers promising for biological interfacing. In the second half, I will show approaches to detect metabolites using conjugated polymers. These include an electronic platform based on an electron transporting (n-type) conjugated polymer. The polymer is engineered to have specific interactions with catalytic enzymes. We employ the n-type semiconducting material in an accumulation mode organic electrochemical transistor (OECT). This micron-scale device detects metabolites without the need of a mediator and shows excellent sensitivity and selectivity. When integrated in an enzymatic biofuel cell, the same polymer serves as the anode, converting the glucose metabolism in an aqueous medium into power. As such, I will highlight the catalytic properties of organic semiconductors and their compatibility with proteins, leading to versatile devices operating at the interface with electrolytes.
BIOGRAPHY: Prof. Sahika Inal faculty webpage.